Synopsis: Breathe In, Breathe Out

Advances in magnetic resonance spectroscopy could remedy the problems caused by movement or unstable fields during a scan.
Synopsis figure
Courtesy S. Chinthalapalli/Indian Institute of Technology

In an NMR measurement, strong and stable magnetic fields are needed to accurately determine the resonant frequencies of nuclear spins. However, sample instabilities and inhomogeneities often cause fluctuations in local fields, which is problematic for high-resolution spectroscopy. Moreover, the highest available magnetic fields can only be generated by pulsed schemes with poorer spatiotemporal stability than that found in persistent superconducting magnets. Now, in a paper in Physical Review Letters, Srinivas Chinthalapalli at the Indian Institute of Technology, New Delhi, and collaborators address this issue with a novel multidimensional NMR method called long-lived-coherence correlation spectroscopy (LLC-COSY) that acquires ultrahigh resolution NMR spectra in highly inhomogeneous or unstable fields.

LLC-COSY relies on coherent superpositions of spin states with very long lifetimes and hence very narrow linewidths. The authors’ method is insensitive to inhomogeneous broadening effects, including those due to local magnetic field fluctuations, and can reduce homogeneous broadening by almost an order of magnitude.

Breathing lungs, pulsating arteries, and surgical implants are among the unstable biological objects amenable to LLC-COSY investigations. LLC-COSY may also enable the use of the highest-field pulsed magnets for high-resolution NMR, opening unexplored frontiers to NMR research. – Matteo Rini


Features

More Features »

Announcements

More Announcements »

Subject Areas

MagnetismBiological PhysicsMedical Physics

Previous Synopsis

Nuclear Physics

Neutron Knockout

Read More »

Next Synopsis

Related Articles

Synopsis: Racing Bacteria
Biological Physics

Synopsis: Racing Bacteria

Bacteria track fast-moving chemical signals by hopping from one chemically favorable region to another. Read More »

Synopsis: Revealing a Hidden Spin Polarization
Condensed Matter Physics

Synopsis: Revealing a Hidden Spin Polarization

Photoemission spectroscopy has detected two different populations of spin-polarized electrons that are “hidden” within a layered, graphene-like material. Read More »

Synopsis: Cell Sensing Improves in a Loose Crowd
Biological Physics

Synopsis: Cell Sensing Improves in a Loose Crowd

Cells that communicate with each other can measure chemical concentrations with higher precision if they spread out into a sparse configuration.   Read More »

More Articles